UCOPE

This study has completed

UCOPE (Understanding Cognition, Oxytocin and Pain in Elders) is no longer enrolling participants. The study completed on December 19, 2024. The contact details below are kept for the record and are no longer monitored for recruitment.

The full study record remains public on ClinicalTrials.gov: NCT03878589.

Interested in taking part in pain research at UF? Join the PRICE research registry and we can contact you about studies you may be eligible for.


Study Name: Understanding Cognition, Oxytocin and Pain in Elders (UCOPE)

Purpose of the study

This project examines the effect of Oxytocin on chronic pain in older adults with knee osteoarthritis.

Who is eligible?

People 55 years of age and older with knee pain.

What will happen if I participate?

The initial screening visit will be about one hour. At home, you will take oxytocin nasal spray and complete weekly check-ins with the study team. There are several visits to UF’s campus including a brain MRI. Those visits will last approximately 2-2.5 hours each.

Contact Information

To find out more contact the UCOPE study team at 352-294-8582, or via email at ucope@ad.ufl.edu


Research Team

Principal Investigator: Yenisel Cruz-Almeida Ph.D., MSPH, UF College of Dentistry, and Natalie Ebner, Ph.D., UF College of Liberal Arts and Sciences.
Study Coordinator: Soamy Montesino Goicolea