This Week At PRICE

Study Published Surrounding Link Between Disposition and Pain


Do dispositional traits, predisposing biological factors also known as temperament, explain individual differences the experience of pain and physical functioning? Researchers at PRICE endeavored to find out.

Researchers at PRICE including Angela Mickle, Dr. Roland Staud and Dr. Kimberly Sibille measured the association between dispositional traits, the infrastructure from which an individual interprets and interacts with the environment, and a radiographic measure of knee osteoarthritis, Kellgren-Lawrence (KL) scores, and pain and physical function. Commonly, KL scores do not correlate well with patient reported pain and function. It was found that a combined consideration of an individual’s dispositional traits and their KL scores helped explain the individual differences observed in pain and function.

While further research is ongoing, understanding an individual’s dispositional traits may help healthcare professionals tailor treatment plans for to better manage knee pain and improve quality of life.

The article “Dispositional traits help explain individual differences in relationships between a radiographic knee osteoarthritis measure, pain and physical function” has been published in Therapeutic Advances in Musculoskeletal Disease.

PRICE Affiliate Receives Award


Congratulations to Larisa Cavallari, who has been been named the recipient of the 2024 American Society for Clinical Pharmacology and Therapeutics, or ASCPT, Malle Jurima-Romet Mid-Career Leadership Award!

the award honors those in the field of clinical pharmacology who are at least 10 years post-training and have demonstrated exceptional and ongoing leadership, remarkable scientific achievements in their area of practice and a commitment to the future of clinical pharmacology and translational medicine. Cavallari, who serves as director of the UF Health Precision Medicine Program and co-director of the UF Center for Pharmacogenomics and Precision Medicine, has demonstrated leadership on a national scale in a host of ways.

Learn more here!

New Review Covering The Importance of Iron


Iron is a mineral that the body needs for growth, development as well as many physiological processes such as bioenergetics, immune function as well as the production of hemoglobin, a protein in red blood cells that carries oxygen from the lunges to other parts of the body.

As we age, healthy levels of iron often becomes more difficult to maintain due to changes in dietary habits and chronic diseases, amongst other things.

A review article, “Iron homeostasis in older adults: balancing nutritional requirements and health risks” which has recently been published in The Journal of Nutrition Health and Aging.

This review article, co-authored by Javier Tamargo, alongside fellow researchers at the Department of Physiology and Aging, provides a comprehensive overview of the forms, sources and metabolism of dietary iron as well as nutritional guidelines and strategies to maintain iron balance in older adults.


Access the article here!