This Week At PRICE

New Study Looks into Effectiveness of Mediterranean Ketogenic Nutrition


A new study recently published in Journal of Pain Research aims to assess the effectiveness of a Mediterranean Ketogenic Nutrition Adherence Program and its potential to assist in managing pain in older adults with mild cognitive impairment.

The Mediterranean Ketogenic Nutrition Adherence program involves a hybrid dietary approach that combines both the Mediterranean diet and the ketogenic diet that involves avoiding high-carb foods and emphasizes healthy fats, lean proteins, nutrient-dense foods and non-starchy vegetables.

In the study, participants were randomly divided into two separate groups and had their pain levels measured. What was found was that, while adhering to the diet program, both groups experienced significant reductions in pain!

The article, “Addressing Pain Using a Mediterranean Ketogenic Nutrition Program in Older Adults with Mild Cognitive Impairment” which was co-authored by Yenisel Cruz-Almeida, can be found here!

New Research on Opioids and Link to Emergency Visits


How does taking certain medications together affect pain management? Can mixing different pain medications together bring on worse results than taking a single one?

Some opioids are processed in the body by an enzyme called CYP2D6. Certain medications can block this enzyme. These medications are known as CYP2D6 inhibitors.

In a recent study, researchers at the University of Florida, including Roger Fillingim, found that individuals who took CYP2D6 inhibitors with opioids were more likely to visit the emergency department for pain-related issues compared to those who didn’t mix the two medications!

Although the main call to action of the study is towards prescribers of pain medication to consider the efficacy of prescribing certain pain medications together, the following link lists examples of CYP2D6 inhibitors.

The full article, titled, “Use of CYP2D6 Inhibitors with CYP2D6 Opioids: Association with Emergency Department Visits for Pain” has been published in Clinical Pharmacology & Therapeutics.