Members of PRICE Author Chapter of Upcoming Text
Congratulations to Mark Bishop, who, alongside Meryl Alappattu, Joel Bialosky and Eric Chaconas, authored the chapter Manual Therapy: Theories, Principles, and Evidence in the upcoming text, Physical Rehabilitation for Musculoskeletal Conditions!
New Publication On The Relationship Between Genetics and Prescriptions
Personalizing opioid prescriptions based on genetic testing and awareness of drug interactions might lead to better pain control and fewer emergency visits.
Researchers including Noor Nahid, Caitrin McDonough and Roger Fillingim found this out by looking at over 31,000 adults who were prescribed opioids that need to be processed by a specific liver enzyme called CYP2D6 (which helps turn these drugs into their active, pain-relieving forms). Some people naturally have lower CYP2D6 activity due to their genes, and others can have it reduced by certain medications.
The study found that individuals with reduced activity of a liver enzyme called CYP2D6 (thanks to genetics or other meds) had more ER visits for pain even while on opioids.
Find out more in the article, “CYP2D6 Phenotypes and Emergency Department Visits Among Patients Receiving Opioid Treatment” which has been published in JAMA Network Open!