Opioid and Anesthesia influence on Cancer Survivorship

Hosted by PRICE & IOA – Presented By Dr. Monika Patel

Monika Patel, M.D.
Assistant Professor
Department of Anesthesiology
Division of Pain Management

Join PRICE and the Institute on Aging and for a discussion on the influences of opioids and anesthetics on cancer survivorship with UF Health Jacksonville’s Dr. Monika Patel.  She is fellowship-trained in pain medicine from the University of Texas M.D. Anderson Cancer Center in Houston, specializing in interventional pain management. While interested in all aspects of pain medicine, her training has an emphasis on treating spinal and cancer-related pain.

Advance Zoom Registration Required

LECTURE OBJECTIVES

  • Key targets of the immune system and angiogenesis that trigger tumor growth and metastasis, specific factors essential for primary to secondary metastasis that are influenced by pain medications
  • Review of opioid effect on tumor angiogenesis through mu opioid receptor, pathways of angiogenesis, NK-cell cytotoxicity effect
  • Review of volatile anesthetics (Isoflurane, halothane, N2O), non-volatile anesthetics (ketamine and propofol), local anesthetics (lidocaine and bupivacaine), NSAIDS (COX-2 block) effect on angiogenesis and immunity on tumor metastasis and survival from in-vitro, animal and human studies
  • Review of anesthetic technique (regional anesthesia, general anesthesia, spinal anesthesia, IV anesthesia) effect on Breast, Ovarian, Prostate and Colon Cancer on cancer survivorship based on literature review.  Very few studies on other types of cancers so not able to review.
  • Gaps in research that limit clinical guideline development.